Image of Prof Glyn Hobbs

Prof Glyn Hobbs

Pharmacy and Biomolecular Sciences

Faculty of Science

Email: G.Hobbs@ljmu.ac.uk

Telephone: 0151 231 2198

Journal article

Vinayavekhin N, Wattanophas T, Murphy MF, Vangnai AS, Hobbs G. 2024. Metabolomics responses and tolerance of Pseudomonas aeruginosa under acoustic vibration stress Shastry RP. PLoS One, 19 :1-19 DOI Author Url Publisher Url Public Url

Almatrood W, Nakouti I, Hobbs G. 2022. Microtiter plate with built-in oxygen sensors: a novel approach to investigate the dynamics of Pseudomonas aeruginosa growth suppression in the presence of divalent cations and antibiotics Archives of Microbiology, 204 DOI Author Url Publisher Url Public Url

Wainwright J, Hobbs G, Nakouti I. 2021. Persister cells: formation, resuscitation and combative therapies. Archives of Microbiology, DOI Author Url Publisher Url Public Url

Cubas-Atienzar AI, Williams CT, Karkey A, Dongol S, Sulochana M, Rajendra S, Hobbs G, Evans K, Musicha P, Feasey N, Cuevas LE, Adams ER, Edwards T. 2021. A Novel Air-Dried Multiplex High Resolution Melt Assay for the Detection of Extended Spectrum Beta-Lactamase and Carbapenemase Genes. Journal of Global Antimicrobial Resistance, 27 :123-131 DOI Author Url Publisher Url Public Url

Edwards T, Williams C, Teethaisong Y, Sealey J, Sasaki S, Hobbs G, Cuevas LE, Evans K, Adams ER. 2020. A highly multiplexed melt-curve assay for detecting the most prevalent carbapenemase, ESBL, and AmpC genes DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, 97 DOI Author Url Publisher Url

Haosagul S, Prommeenate P, Hobbs G, Pisutpaisal N. 2020. Sulfur-oxidizing bacteria in full-scale biogas cleanup system of ethanol industry RENEWABLE ENERGY, 150 :965-972 DOI Author Url Publisher Url

Haosagul S, Prommeenate P, Hobbs G, Pisutpaisal N. 2020. Sulfide-oxidizing bacteria community in full-scale bioscrubber treating H2S in biogas from swine anaerobic digester RENEWABLE ENERGY, 150 :973-980 DOI Author Url Publisher Url

Teethaisong Y, Nakouti I, Evans K, Eumkeb G, Hobbs G. 2019. Nitro-Carba test, a novel and simple chromogenic phenotypic method for rapid screening of carbapeneamase-producing Enterobacteriaceae. Journal of Global Antimicrobial Resistance, 18 :22-25 DOI Author Url Publisher Url Public Url

Morrison J, Watts G, Hobbs G, Dawnay N. 2018. Field-based detection of biological samples for forensic analysis: Established techniques, novel tools, and future innovations. Forensic Science International, 285 :147-160 DOI Author Url Publisher Url Public Url

Edwards T, Sasaki S, Williams C, Hobbs G, Feasey NA, Evans K, Adams ER. 2018. Speciation of common Gram-negative pathogens using a highly multiplexed high resolution melt curve assay Scientific Reports, 8 DOI Author Url Publisher Url Public Url

Teethaisong Y, Hobbs G, Nakouti I, Evans K, Eumkeb G. 2018. A nitrocefin disc supplemented with ertapenem for rapid screening of carbapenemase-producing Enterobacteriaceae Diagnostic Microbiology and Infectious Disease, DOI Author Url Publisher Url Public Url

Teethaisong Y, Pimchan T, Srisawat R, Hobbs G, Eumkeb G. 2017. Boesenbergia rotunda (L.) Mansf. extract potentiate the antibacterial activity of some β-lactams against β-lactam-resistant Staphylococci. Journal of Global Antimicrobial Resistance, DOI Author Url Publisher Url Public Url

Teethaisong Y, Evans K, Nakouti I, Tiamyom K, Ketudat-Cairns JR, Hobbs G, Eumkeb G. 2017. The performance of a resazurin chromogenic agar plate with a combined disc method for rapid screening of extended-spectrum-β-lactamases, AmpC β-lactamases and co-β-lactamases in Enterobacteriaceae Microbiology and Immunology, 61 :297-304 DOI Author Url Publisher Url Public Url

Khan KM, Nahar L, Mannan A, Arfan M, Khan GA, Hobbs G, Sarker SD. 2017. Evaluation of Resazurin Microtiter Plate Assay and HPLCPhotodiode Array Analysis of the Roots of Asparagus adscendens Natural Product Research, DOI Author Url Publisher Url Public Url

Nakouti I, Hobbs G, Teethaisong Y, Phipps D. 2017. A demonstration of athermal effects of continuous microwave irradiation on the growth and antibiotic sensitivity of Pseudomonas aeruginosa PAO1. Biotechnology Progress, 33 :37-44 DOI Author Url Publisher Url Public Url

Phitaktim S, Chomnawang M, Sirichaiwetchakoon K, Dunkhunthod B, Hobbs G, Eumkeb G. 2016. Synergism and the mechanism of action of the combination of alpha-mangostin isolated from Garcinia mangostana L. and oxacillin against an oxacillin-resistant Staphylococcus saprophyticus BMC MICROBIOLOGY, 16 DOI Author Url Publisher Url Public Url

Teethaisong Y, Eumkeb G, Chumnarnsilpa S, Autarkool N, Hobson J, Nakouti I, Hobbs G, Evans K. 2016. Phenotypic detection of AmpC β-lactamases, extended-spectrum- β-lactamases and metallo-β-lactamases in Enterobacteriaceae using a resazurin microtitre assay with inhibitor-based methods. Journal of Medical Microbiology, DOI Author Url Publisher Url Public Url

Murphy MF, Edwards T, Hobbs G, Shepherd J, Bezombes F. 2016. Acoustic Vibration Can Enhance Bacterial Biofilm Formation Journal of Bioscience and Bioengineering, DOI Author Url Publisher Url Public Url

Teethaisong Y, Eumkeb G, Nakouti I, Evans K, Hobbs G. 2016. A combined disc method with resazurin agar plate assay for early phenotypic screening of KPC, MBL and OXA-48 carbapenemases among Enterobacteriaceae. Journal of Applied Microbiology, DOI Author Url Publisher Url Public Url

Nakouti I, Hobbs G. 2015. The Application of an On-Line Optical Sensor to Measure Biomass of a Filamentous Bioprocess Fermentation, 1 :79-85 DOI Publisher Url Public Url

Saull J, Duggan C, Hobbs G, Edwards T. 2015. The detection of Atlantic cod (Gadus morhua) using loop mediated isothermal amplification in conjunction with a simplified DNA extraction process Food Control, 59 :306-313 DOI Author Url Publisher Url Public Url

Edwards T, Burke P, Smalley HB, Gillies L, Longhurst D, Vipond B, Hobbs G. 2015. Loop-mediated isothermal amplification (LAMP) for the rapid detection of Mycoplasma genitalium Diagnostic Microbiology and Infectious Disease, 83 :13-17 DOI Author Url Publisher Url Public Url

Edwards T, Burke P, Smalley H, Hobbs G. 2014. Trichomonas vaginalis: Clinical relevance, pathogenicity and diagnosis Critical Reviews in Microbiology, 42 DOI Author Url Publisher Url Public Url

Edwards T, Burke PA, Smalley HB, Gillies L, Hobbs G. 2014. Loop-Mediated Isothermal Amplification Test for Detection of Neisseria gonorrhoeae in Urine Samples and Tolerance of the Assay to the Presence of Urea Journal of Clinical Microbiology, 52 :6163-6165 DOI Author Url Publisher Url Public Url

Nakouti I, Hobbs G. 2014. The Use of Proteolytic Activity to Evaluate Meat Tenderising Agents. International Journal of Sciences, 3 :61-63

Nakouti I, Hobbs G. 2014. Incorporation of L-lysine and 2,2'-dipyridyl in the growth media promotes desferrioxamine E production by an actinobacterium. World J Microbiol Biotechnol, 30 :331-334 DOI Author Url Publisher Url

Nakouti I, Hobbs G. 2013. A new approach to studying ion uptake by actinomycetes. J Basic Microbiol, 53 :913-916 DOI Author Url Publisher Url

Nakouti I, Sihanonth P, Palaga T, Hobbs G. 2013. Effect of a siderophore producer on animal cell apoptosis: a possible role as anti-cancer agent. International Journal of Pharma Medicine and Biological Sciences, 2 :1-5 Publisher Url Public Url

Nakouti I, Sihanonth P, Hobbs G. 2012. A new approach to isolating siderophore-producing actinobacteria. Lett Appl Microbiol, 55 :68-72 DOI Author Url Publisher Url Public Url

Nakouti I, Hobbs G. 2012. Characterisation of Five Siderophore Producing Actinomycetes from Soil Samples and the Use of Antibiotic Resistance to Differentiate the Isolates International Journal of Agriculture Sciences, 4 :44-51 Publisher Url

Nakouti I, Hobbs G. 2012. Consumption of Phosphorus and Production of Alkaline Phosphatase during Growth of Streptomyces coelicolor in a Rich Medium International Journal of Microbiology Research, 4 :164-167 DOI Publisher Url

Bamber AI, Fitzsimmons K, Cunniffe JG, Beasor CC, Mackintosh CA, Hobbs G. 2012. Diagnosis of Clostridium difficile-associated disease: examination of multiple algorithms using toxin EIA, glutamate dehydrogenase EIA and loop-mediated isothermal amplification BRITISH JOURNAL OF BIOMEDICAL SCIENCE, 69 :112-118 DOI Author Url Publisher Url

Gaskell EE, Sihanonth P, Rostron C, Hutcheon GA, Hobbs G. 2010. Isolation and identification of mucinolytic actinomycetes. Antonie Van Leeuwenhoek, 97 :211-220 DOI Author Url Publisher Url

Watthanakulpanich D, Smith HV, Hobbs G, Whalley AJ, Billington D. 2008. Application of Toxocara canis excretory-secretory antigens and IgG subclass antibodies (IgG1-4) in serodiagnostic assays of human toxocariasis. Acta Trop, 106 :90-95 DOI Author Url Publisher Url

Gaskell EE, Hobbs G, Rostron C, Hutcheon GA. 2008. Encapsulation and release of alpha-chymotrypsin from poly(glycerol adipate-co-omega-pentadecalactone) microparticles. J Microencapsul, 25 :187-195 DOI Author Url Publisher Url Public Url

Hoskisson PA, Hobbs G. 2006. One size doesn't fit all MICROBIOLOGY-SGM, 152 :1891-1891 DOI Author Url Publisher Url

Hoskisson PA, Sharples GP, Hobbs G. 2006. Differentiation and protease production in Micromonospora echinospora (ATCC 15837). Antonie Van Leeuwenhoek, 89 :191-195 DOI Author Url Publisher Url

Hoskisson PA, Hobbs G. 2005. Continuous culture - making a comeback? MICROBIOLOGY-SGM, 151 :3153-3159 DOI Author Url Publisher Url

Hoskisson PA, England R, Sharples GP, Hobbs G. 2004. Modulation of glycogen and trehalose levels in Micromonospora echinospora (ATCC 15837). Antonie Van Leeuwenhoek, 86 :225-233 DOI Author Url Publisher Url

Hoskisson PA, Sharples GP, Hobbs G. 2003. The importance of amino acids as carbon sources for Micromonospora echinospora (ATCC 15837). Lett Appl Microbiol, 36 :268-271 DOI Author Url Publisher Url

Hoskisson PA, Hobbs G, Sharples GP. 2001. Antibiotic production, accumulation of intracellular carbon reserves, and sporulation in Micromonospora echinospora (ATCC 15837). Can J Microbiol, 47 :148-152 DOI Author Url Publisher Url

Hoskisson PA, Makin V, Taylor H, Sharples GP, Hobbs G. 2001. Intracellular protease activity during the growth of Streptomyces coelicolor BIOTECHNOLOGY LETTERS, 23 :185-187 DOI Author Url Publisher Url

Hoskisson PA, Hobbs G, Sharples GP. 2000. Response of Micromonospora echinospora (NCIMB 12744) spores to heat treatment with evidence of a heat activation phenomenon. Lett Appl Microbiol, 30 :114-117 DOI Author Url Publisher Url

Karandikar A, Sharples GP, Hobbs G. 1997. Differentiation of Streptomyces coelicolor A3(2) under nitrate-limited conditions MICROBIOLOGY-SGM, 143 :3581-3590 DOI Author Url Publisher Url

Hayes A, Hobbs G, Smith CP, Oliver SG, Butler PR. 1997. Environmental signals triggering methylenomycin production by Streptomyces coelicolor A3(2). J Bacteriol, 179 :5511-5515 DOI Author Url Publisher Url

Karandikar A, Sharples GP, Hobbs G. 1996. Influence of medium composition on sporulation by Streptomyces coelicolor A3(2) grown on defined solid media. BIOTECHNOLOGY TECHNIQUES, 10 :79-82 DOI Author Url Publisher Url

Obanye AIC, Hobbs G, Gardner DCJ, Oliver SG. 1996. Correlation between carbon flux through the pentose phosphate pathway and production of the antibiotic methylenomycin in Streptomyces coelicolor A3(2) MICROBIOLOGY-SGM, 142 :133-137 DOI Author Url Publisher Url

Musialowski MS, Flett F, Scott GB, Hobbs G, Smith CP, Oliver SG. 1994. Functional evidence that the principal DNA replication origin of the Streptomyces coelicolor chromosome is close to the dnaA-gyrB region Journal of Bacteriology, 176 :5123-5125 DOI Publisher Url

HOBBS G, FRASER CM, GARDINER DCJ, CULLUM JA, OLIVER SG. 1988. DISPERSED GROWTH OF STREPTOMYCES IN LIQUID CULTURES HEREDITY, 61 :312-313 Author Url

HOBBS G, GRIFFITHS AJ, HANN AOC. 1986. X-RAY-MICROANALYSIS OF ELECTRON-DENSE BODIES IN CLADOSPORIUM-RESINAE FEMS MICROBIOLOGY LETTERS, 33 :285-288 DOI Author Url Publisher Url

Edwards T, Burke P, Smalley H, Hobbs G. Trichomonas vaginalis:Clinical relevance,pathogenicity and diagnosis Critical Reviews in Microbiology,

Conference publication

Gaskell E, Hobbs G, Rostron C, Hutcheon GA. 2006. Encapsulation of mucinolytic enzymes for treatment of cystic fibrosis JOURNAL OF PHARMACY AND PHARMACOLOGY, 58 :A67-A67 Author Url

Gaskell E, Hobbs G, Rostron C, Hutcheon G. 2005. Use of functional polymers for treatment of pulmonary cystic fibrosis JOURNAL OF PHARMACY AND PHARMACOLOGY, 57 :S5-S5 Author Url

Gaskell E, Hobbs G, Rostron C, Hutcheon G. 2005. Use of functional polymers for treatment of pulmonary cystic fibrosis JOURNAL OF PHARMACY AND PHARMACOLOGY, 57 :S60-S60 Author Url

Duncan PJ, Jenkins HA, Hobbs G. 1997. The effect of hyperosmotic conditions on growth and recombinant protein expression by NS0 myeloma cells in culture GENETIC ENGINEER AND BIOTECHNOLOGIST, 7th Annual Scientific Meeting of ESACT UK 17 :75-78 Author Url

Research Grants Awarded:

Society for Applied Microbiology, Targeting Mycetoma with Organosulphur compounds, Dr Glyn Hobbs (Main applicant), Grant value (£): £2500, Duration of research project: 10 weeks. 2016

BBSRC IBCarb, Enhancement of biofilms by acoustics, Mark Murphy, Grant value (£): £10,000, Duration of research project: 6 months. 2016

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