Thesis/Dissertation

Thompson C. 2023. Development of Tools to Support the Application of Physiologically-Based Kinetic Modelling in Safety Assessment Madden J, Webb S, Penson P. Public Url

Conference publication

Madden J, Thompson C, Paini A. 2022. Criteria for selecting physiologically-based kinetic models for use in developing new models for data-poor analogues via a read-across approach Toxicology Letters, XVIth International Congress of Toxicology (ICT 2022), Maastricht, The Netherlands 368S1 :S268-S269

Thompson C, Webb SD, Leedale J, Penson PE, Paini A, Ebbrell D, Madden J. 2022. P17-04 An automated tool for selection of chemical analogues to facilitate development of new physiologically-based kinetic models using a read-across approach XVIth International Congress of Toxicology (ICT 2022) DOI Publisher Url

Thompson C, Webb SD, Leedale J, Penson P, Madden J, Paini A. 2022. Development of a Tool to Assist Selection of Chemical Analogues to Facilitate Development of New Physiologically Based Kinetic Models Using a Read-Across Approach The Toxicologist: Supplement to Toxicological Sciences, Society of Toxicology (SOT) 61st Annual Meeting & TOXEXPO :448-448 Publisher Url

Thompson C, Penson P, Madden J. 2022. Development of a Database of Physiologically-based Kinetic Models Alternatives to Laboratory Animals, JRC Summer School 49 :291-292

Madden J, Thompson C, Webb S, Ebbrell D, Penson P, Tan Y-M, Paini A. 2021. Tools to support application of physiologically based kinetic modelling in safety assessment Altex Proceedings, 11th World Congress on Alternatives and Animal Use in the Life Sciences 49 :52-52 Publisher Url

Thompson C, Webb S, Penson P, Sneddon A, Madden J. 2021. Assessing the reproducibility of published physiologically based kinetic models ALTEX Proceedings, 11th World Congress on Alternatives and Animal Use in the Life Sciences 9 :248-248

Journal article

Thompson C, Firman JW, Goldsmith M, Grulke C, Tan Y-M, Paini A, Penson P, Sayre R, Webb S, Madden JC. 2021. A systematic review of published physiologically-based kinetic models and an assessment of their chemical space coverage Alternatives to Laboratory Animals, 49 :197-208 DOI Author Url Publisher Url Public Url

Other

Thompson C, Penson P, Madden J. 2020. Research Protocol Registration: Systematic review to determine the chemical space of existing physiologically-based kinetic (PBK) models PROSPERO 2020 CRD42020171130, Publisher Url

Dataset

Sayre R, Grulke C, Tan Y-M, Madden J, Thompson C, Webb S, Penson P. 2019. Existing physiologically-based kinetic (PBK) models, identified via PubMed searches (with associated EndNote library) DOI

Chapters

Madden J, Thompson C. Pharmacokinetic Tools and Applications Benfenati E. In Silico Methods for Predicting Drug Toxicity DOI Author Url Publisher Url